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Recommendations for Follow Up After OneTest™

Leukemia

Symptoms:

  • Fatigue or weakness
  • Fever or chills
  • Frequent infections
  • Unexplained weight loss
  • Easy bruising or bleeding
  • Swollen lymph nodes, especially in the neck or armpits
  • Enlarged liver or spleen
  • Bone pain or tenderness
  • Night sweats
  • Shortness of breath

Signs:

  • Enlarged liver or spleen
  • Enlarged lymph nodes, especially in the neck or armpits
  • Petechiae (small red or purple spots on the skin)
  • Ecchymosis (bruising)
  • Pallor (pale skin)

Risk Factors

  • Previous Cancer Treatment: Previous treatment with chemotherapy or radiation therapy increases the risk.
  • Genetic disorders: Certain genetic disorder, such as Down Syndrome, increase the risk.
  • Family History: Having a first-degree relative (parent, sibling, or child) with leukemia increases the risk.
  • Smoking: Smoking increases the risk of acute myeloid leukemia (AML).
  • Exposure to certain chemicals: Exposure to benzene or certain chemotherapy drug increases the risk.
  • Exposure to high levels of radiation: Exposure to high levels of radiation, such as from a nuclear accident or atomic bomb, increases the risk.
  • Certain blood disorders: certain blood disorders, such as myelodysplastic syndrome (MDS) or myeloproliferative neoplasms (MPNs), increase the risk

Other Screening Tools:

  • Complete blood count (CBC): Recommended for individuals with risk factors for leukemia or symptoms suggestive of leukemia.
  • Bone marrow biopsy: Recommended if abnormalities are detected during a CBC or if leukemia is suspected.
  • Imaging tests (CT scan, MRI): Recommended for individuals with risk factors for leukemia or symptoms suggestive of leukemia

Next Exam(s) To Do

  • Bone Marrow Biopsy: If OneTest indicates elevated predictive risk for leukemia, a bone marrow biopsy would be performed for further evaluation. This procedure involves taking a small sample of bone marrow from the hip bone or sternum and examining it under a microscope to look for abnormal cells.
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