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Recommendations for Follow Up After OneTest™

Gastric (Stomach) Cancer

Elevated Biomarkers

CEA

Symptoms:

  • Persistent abdominal pain or discomfort, especially in the upper abdomen
  • Nausea or vomiting, especially after eating.
  • Loss of appetite
  • Unexplained weight loss
  • Feeling of fullness or bloating after eating small amounts.
  • Difficulty swalling
  • Indigestion or heartburn that doesn’t go away
  • Fatigue

Signs:

  • Enlarged lymph nodes in the abdomen
  • Palpable mass in the abdomen

Risk Factors

  • Helicobacter pylori infection: A bacterial infection that can cause chronic inflammation of the stomach lining and increase the risk of gastric cancer.
  • Family History: Having a first-degree relative (parent, sibling, or child) with gastric cancer increases the risk
  • Previous Stomach Surgery: previous surgery to remove part of the stomach (gastrectomy) or to treat peptic ulcers increases the risk
  • Smoking: smoking increases the risk of gastric cancer
  • Diet: A diet high in smoked, salted, or pickled foods; low in fruits and vegetables; or high in processed meats may increase the risk.
  • Obesity: Being overweight or obese may increase the risk.
  • Pernicious anemia: A condition in which the body can’t absorb enough vitamin B12, which increases the risk.
  • Chronic gastritis: chronic inflammation of the stomach lining increases the risk.

Other Screening Tools:

  • Upper endoscopy (esophagogastroduodenoscopy or EGD): Recommended for individuals with risk factors for gastric cancer or symptoms suggestive of gastric cancer.
  • Biopsy: Recommended if abnormalities are detected during an upper endoscopy
  • Imaging tests (CT scan, MRI): Recommended for individuals with risk factors for gastric cancer or symptoms suggestive of gastric cancer

Next Exam(s) To Do

  • Upper endoscopy (EGD): If OneTest indicates elevated predictive risk for gastric cancer, an upper endoscopy would be performed for further evaluation. This procedure allows for visualization of the stomach lining and the collection of tissue samples (biopsies) for analysis
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