Colorectal Cancer
Elevated Biomarkers
CEA
CA 19-9
CA 125
Symptoms:
- Changes in bowel habits such as diarrhea or constipation
- Rectal bleeding or blood in the stool
- Persistent abdominal discomforts like cramps, gas, or pain
- Weakness or fatigue
- Unexplained weight loss
- Feeling that the bowel doesn’t empty completely
- Nausea or vomiting
Signs:
- Anemia
- Visible blood in the stool
- Palpable mass in the abdomen
Risk Factors
- Age 50 and over
- Personal or family history of colorectal cancer or polyps
- Inflammatory bowel disease (Crohn’s disease or ulcerative colitis)
- Certain genetic syndromes (Familial Adenomatous Polyposis (FAP), Lynch syndrome)
- Sedentary lifestyle
- Obesity
- Smoking
- Heavy alcohol consumption
Other Screening Tools:
- Colonoscopy: Typically recommended every 10 years starting at age 50.
- Fecal occult blood test (FOBT) or fecal immunochemical test (FIT): Recommended annually.
- Flexible sigmoidoscopy: Recommended every 5 years along with FIT every 3
years. - Virtual colonoscopy (CT colonography): Recommended every 5 years.
Next Exam(s) To Do
- Colonoscopy: This is the gold standard for detecting colorectal cancer and is
recommended for further evaluation if OneTest indicates elevated predictive
risk. It allows for visualization of the entire colon and rectum, and the removal
of any precancerous polyps.
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